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CD74(CLIP/813), CF405S conjugate, 0.1mg/mL [26628-22-8]

CD74(CLIP/813), CF405S conjugate, 0.1mg/mL [26628-22-8]

BNC040813
Biotium
ApplicationsFlow Cytometry, ImmunoFluorescence, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
Product group Antibodies
ReactivityBovine, Human, Mouse
TargetCD74
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Overview

  • Supplier
    Biotium
  • Product Name
    CD74(CLIP/813), CF405S conjugate, 0.1mg/mL
  • Delivery Days Customer
    9
  • Applications
    Flow Cytometry, ImmunoFluorescence, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
  • Certification
    Research Use Only
  • Clonality
    Monoclonal
  • Clone ID
    CLIP/813
  • Concentration
    0.1 mg/ml
  • Conjugate
    Other Conjugate
  • Gene ID972
  • Target name
    CD74
  • Target description
    CD74 molecule
  • Target synonyms
    CD74 antigen (invariant polypeptide of major histocompatibility complex, class II antigen-associated); CD74 molecule, major histocompatibility complex, class II invariant chain; DHLAG; gamma chain of class II antigens; HLA class II histocompatibility antigen gamma chain; HLADG; HLA-DR antigens-associated invariant chain; HLA-DR-gamma; Ia-associated invariant chain; Ia-GAMMA; II; MHC HLA-DR gamma chain; p33
  • Host
    Mouse
  • Isotype
    IgG1
  • Scientific Description
    This antibody recognizes a protein of ~35 kDa, identified as CD74. It is a type II transmembrane protein which binds to the peptide binding groove of newly synthesized MHC class II alpha/beta heterodimers and prevents their premature association with endogenous polypeptides. CD74 is expressed primarily by antigen presenting cells, such as B-lymphocytes (from before the pre-B cell stage to before the plasma cell stage), macrophages, and monocytes, and many epithelial cells. Anti-CD74 stains predominantly germinal center lymphocytes and B-cell lymphomas, but rarely T-cell lymphomas. Anti-CD74 has been shown to be useful in differentiating atypical fibroxanthoma (-) from malignant fibrous histiocytoma ( ).Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.
  • Source
    Animal
  • Reactivity
    Bovine, Human, Mouse
  • Storage Instruction
    2°C to 8°C
  • UNSPSC
    12352203