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ProductsBack/CD8 alpha antibody [RPA-T8] (Biotin)
FACS analysis of human peripheral blood lymphocytes using GTX01467-02 CD8 alpha antibody [RPA-T8] (Biotin). Solid lone : primary antibody Dashed line : isotype control antibody amount : 0.125 microg (5 microl)
FACS analysis of human peripheral blood lymphocytes using GTX01467-02 CD8 alpha antibody [RPA-T8] (Biotin). Solid lone : primary antibody Dashed line : isotype control antibody amount : 0.125 microg (5 microl)
FACS analysis of human peripheral blood lymphocytes using GTX01467-02 CD8 alpha antibody [RPA-T8] (Biotin). Solid lone : primary antibody Dashed line : isotype control antibody amount : 0.125 microg (5 microl)

CD8 alpha antibody [RPA-T8] (Biotin)

Research Use Only
GTX01467-02
GeneTex
ApplicationsFlow Cytometry
Product group Antibodies
ReactivityHuman, Monkey, Primate
TargetCD8A
Price on request
Packing Size
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More than 130 suppliers
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Overview

  • Supplier
    GeneTex
  • Product Name
    CD8 alpha antibody [RPA-T8] (Biotin)
  • Delivery Days Customer
    9
  • Applications
    Flow Cytometry
  • Certification
    Research Use Only
  • Clonality
    Monoclonal
  • Clone ID
    RPA-T8
  • Concentration
    0.5 mg/ml
  • Conjugate
    Biotin
  • Gene ID925
  • Target name
    CD8A
  • Target description
    CD8a molecule
  • Target synonyms
    CD8; CD8 antigen, alpha polypeptide (p32); Leu2; Leu2 T-lymphocyte antigen; OKT8 T-cell antigen; p32; T cell co-receptor; T8 T-cell antigen; T-cell antigen Leu2; T-cell surface glycoprotein CD8 alpha chain; T-lymphocyte differentiation antigen T8/Leu-2
  • Host
    Mouse
  • Isotype
    IgG1
  • Scientific Description
    The CD8 antigen is a cell surface glycoprotein found on most cytotoxic T lymphocytes that mediates efficient cell-cell interactions within the immune system. The CD8 antigen acts as a coreceptor with the T-cell receptor on the T lymphocyte to recognize antigens displayed by an antigen presenting cell in the context of class I MHC molecules. The coreceptor functions as either a homodimer composed of two alpha chains or as a heterodimer composed of one alpha and one beta chain. Both alpha and beta chains share significant homology to immunoglobulin variable light chains. This gene encodes the CD8 alpha chain. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Nov 2011]
  • Reactivity
    Human, Monkey, Primate
  • Storage Instruction
    2°C to 8°C
  • UNSPSC
    12352203

References

  • The monocyte Fcgamma receptors FcgammaRI/gamma and FcgammaRIIA differ in their interaction with Syk and with Src-related tyrosine kinases. Huang ZY et al., 2004 Aug, J Leukoc Biol
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  • Early resolution of acute immune activation and induction of PD-1 in SIV-infected sooty mangabeys distinguishes nonpathogenic from pathogenic infection in rhesus macaques. Estes JD et al., 2008 May 15, J Immunol
    Read more
  • Eradication of tumors from a human colon cancer cell line and from ovarian cancer metastases in immunodeficient mice by a single-chain Ep-CAM-/CD3-bispecific antibody construct. Schlereth B et al., 2005 Apr 1, Cancer Res
    Read more
  • Biliary atresia is associated with CD4+ Th1 cell-mediated portal tract inflammation. Mack CL et al., 2004 Jul, Pediatr Res
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  • Polymorphism of murine Fas ligand that affects the biological activity. Kayagaki N et al., 1997 Apr 15, Proc Natl Acad Sci U S A
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  • Cardiac allograft vascular disease. Relationship to microvascular cell surface markers and inflammatory cell phenotypes on endomyocardial biopsy. Deng MC et al., 1995 Mar 15, Circulation
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