Western blot analysis of extracts from HT29 cells using cdc25C(Ab-216) Antibody and the same antibody preincubated with blocking peptide.
Western blot analysis of extracts from HT29 cells using cdc25C(Ab-216) Antibody and the same antibody preincubated with blocking peptide.
CDC25C (Ab-216) Antibody
CSB-PA189566
ApplicationsImmunoFluorescence, Western Blot, ELISA, ImmunoHistoChemistry
Product group Antibodies
ReactivityHuman
TargetCDC25C
Overview
- SupplierCusabio
- Product NameCDC25C (Ab-216) Antibody
- Delivery Days Customer20
- ApplicationsImmunoFluorescence, Western Blot, ELISA, ImmunoHistoChemistry
- CertificationResearch Use Only
- ClonalityPolyclonal
- ConjugateUnconjugated
- Gene ID995
- Target nameCDC25C
- Target descriptioncell division cycle 25C
- Target synonymsCDC25; CDC25 homolog C; dual specificity phosphatase CDC25C; mitosis inducer CDC25; M-phase inducer phosphatase 3; phosphotyrosine phosphatase; PPP1R60; protein phosphatase 1, regulatory subunit 60
- HostRabbit
- IsotypeIgG
- Protein IDP30307
- Protein NameM-phase inducer phosphatase 3
- Scientific Descriptioncdc25C is highly conserved during evolution and it plays a key role in the regulation of cell division. The encodedprotein is a tyrosine phosphatase and belongs to the Cdc25 phosphatase family. It directs dephosphorylation of cyclin B-bound CDC2 and triggers entry into mitosis. It is also thought to suppress p53-induced growth arrest. Multiple alternatively spliced transcript variants of this gene have been described, however, the full-length nature of many of them is not known. Toyoshima-Morimoto F. et al. (2002) EMBO Rep. 3(4): 341-348. Ferguson AM. et al. (2005) Mol Cell Biol. 25(7): 2853-2860. Donzelli M. et al. (2003) EMBO Rep. 4(7): 671-677. Chen F. et al. (2002) Proc Natl Acad Sci U S A. 99(4): 1990-1995.
- ReactivityHuman
- Storage Instruction-20°C or -80°C
- UNSPSC12352203