The image on the left is immunohistochemistry of paraffin-embedded Human lung cancer tissue using CSB-PA617763(CDC27 Antibody) at dilution 1/50, on the right is treated with fusion protein. (Original magnification: x200)
CDC27 Antibody
CSB-PA617763
ApplicationsELISA, ImmunoHistoChemistry
Product group Antibodies
ReactivityHuman
TargetCDC27
Overview
- SupplierCusabio
- Product NameCDC27 Antibody
- Delivery Days Customer20
- ApplicationsELISA, ImmunoHistoChemistry
- CertificationResearch Use Only
- ClonalityPolyclonal
- ConjugateUnconjugated
- Gene ID996
- Target nameCDC27
- Target descriptioncell division cycle 27
- Target synonymsANAPC3; anaphase promoting complex subunit 3; anaphase-promoting complex, protein 3; APC3; CDC27Hs; cell division cycle 27 homolog; cell division cycle protein 27 homolog; D0S1430E; D0S1430E, D17S978E; D17S978E; HNUC; H-NUC; NUC2; nuc2 homolog
- HostRabbit
- IsotypeIgG
- Protein IDP30260
- Protein NameCell division cycle protein 27 homolog
- Scientific DescriptionThe protein encoded by this gene shares strong similarity with Saccharomyces cerevisiae protein Cdc27, and the gene product of Schizosaccharomyces pombe nuc 2. This protein is a component of anaphase-promoting complex (APC), which is composed of eight protein subunits and highly conserved in eucaryotic cells. APC catalyzes the formation of cyclin B-ubiquitin conjugate that is responsible for the ubiquitin-mediated proteolysis of B-type cyclins. This protein and 3 other members of the APC complex contain the TPR (tetratricopeptide repeat), a protein domain important for protein-protein interaction. This protein was shown to interact with mitotic checkpoint proteins including Mad2, p55CDC and BUBR1, and thus may be involved in controlling the timing of mitosis. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
- ReactivityHuman
- Storage Instruction-20°C or -80°C
- UNSPSC12352203