Western blot analysis of extracts from Jurkat/COLO205 cells, using MRCKa antibody.
Western blot analysis of extracts from Jurkat/COLO205 cells, using MRCKa antibody.
CDC42BPA Antibody
CSB-PA019608
ApplicationsImmunoFluorescence, Western Blot, ELISA, ImmunoHistoChemistry
Product group Antibodies
ReactivityHuman
TargetCDC42BPA
Overview
- SupplierCusabio
- Product NameCDC42BPA Antibody
- Delivery Days Customer20
- ApplicationsImmunoFluorescence, Western Blot, ELISA, ImmunoHistoChemistry
- CertificationResearch Use Only
- ClonalityPolyclonal
- ConjugateUnconjugated
- Gene ID8476
- Target nameCDC42BPA
- Target descriptionCDC42 binding protein kinase alpha
- Target synonymsCDC42 binding protein kinase alpha (DMPK-like); CDC42 binding protein kinase beta; MRCK; MRCKA; myotonic dystrophy kinase-related CDC42-binding protein kinase alpha; myotonic dystrophy protein kinase-like alpha; PK428; serine/threonine-protein kinase MRCK alpha; ser-thr protein kinase PK428; ser-thr protein kinase related to the myotonic dystrophy protein kinase
- HostRabbit
- IsotypeIgG
- Protein IDQ5VT25
- Protein NameSerine/threonine-protein kinase MRCK alpha
- Scientific DescriptionSerine/threonine-protein kinase which is an important downstream effector of CDC42 and plays a role in the regulation of cytoskeleton reorganization and cell migration. Regulates actin cytoskeletal reorganization via phosphorylation of PPP1R12C and MYL9/MLC2. In concert with MYO18A and LURAP1, is involved in modulating lamellar actomyosin retrograde flow that is crucial to cell protrusion and migration. Phosphorylates: PPP1R12A, LIMK1 and LIMK2. May play a role in TFRC-mediated iron uptake. Wilkinson S., Nat. Cell Biol. 7:255-261(2005). Totoki Y., Submitted (MAR-2005) to the EMBL/GenBank/DDBJ databases. Bechtel S., BMC Genomics 8:399-399(2007).
- ReactivityHuman
- Storage Instruction-20°C or -80°C
- UNSPSC12352203