
Western blot analysis of extracts from COLO cells, using MRCKB antibody.
CDC42BPB Antibody
CSB-PA936608
ApplicationsWestern Blot, ELISA, ImmunoHistoChemistry
Product group Antibodies
ReactivityHuman, Mouse, Rat
TargetCDC42BPB
Overview
- SupplierCusabio
- Product NameCDC42BPB Antibody
- Delivery Days Customer20
- ApplicationsWestern Blot, ELISA, ImmunoHistoChemistry
- CertificationResearch Use Only
- ClonalityPolyclonal
- ConjugateUnconjugated
- Gene ID9578
- Target nameCDC42BPB
- Target descriptionCDC42 binding protein kinase beta
- Target synonymsCDC42 binding protein kinase beta (DMPK-like); CDC42BP-beta; DMPK-like beta; MRCK beta; MRCKB; myotonic dystrophy kinase-related CDC42-binding kinase beta; myotonic dystrophy protein kinase-like beta; serine/threonine-protein kinase MRCK beta
- HostRabbit
- IsotypeIgG
- Protein IDQ9Y5S2
- Protein NameSerine/threonine-protein kinase MRCK beta
- Scientific DescriptionSerine/threonine-protein kinase which is an important downstream effector of CDC42 and plays a role in the regulation of cytoskeleton reorganization and cell migration. Regulates actin cytoskeletal reorganization via phosphorylation of PPP1R12C and MYL9/MLC2. In concert with MYO18A and LURAP1, is involved in modulating lamellar actomyosin retrograde flow that is crucial to cell protrusion and migration. Phosphorylates PPP1R12A. Nakajima D., DNA Res. 9:99-106(2002). Olsen J.V., Cell 127:635-648(2006). Hirosawa M., DNA Res. 6:329-336(1999).
- ReactivityHuman, Mouse, Rat
- Storage Instruction-20°C or -80°C
- UNSPSC12352203