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CDH12 Polyclonal Antibody

Research Use Only
RD219682A
Reddot Biotech
ApplicationsELISA, ImmunoHistoChemistry
Product group Antibodies
ReactivityHuman, Mouse
TargetCDH12
Price on request
Packing Size
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Overview

  • Supplier
    Reddot Biotech
  • Product Name
    CDH12 Polyclonal Antibody
  • Delivery Days Customer
    5
  • Applications
    ELISA, ImmunoHistoChemistry
  • Certification
    Research Use Only
  • Clonality
    Polyclonal
  • Concentration
    1.74 mg/ml
  • Conjugate
    Unconjugated
  • Gene ID1010
  • Target name
    CDH12
  • Target description
    cadherin 12
  • Target synonyms
    brain-cadherin; Br-cadherin; cadherin, neural type, 2; cadherin-12; CDHB; N-cadherin 2; neural type cadherin 2; neuronal cadherin 2
  • Host
    Rabbit
  • Isotype
    IgG
  • Scientific Description
    This gene encodes a type II classical cadherin of the cadherin superfamily. Alternative splicing of this gene results in multiple transcript variants. At least one of these variants encodes a preproprotein that is proteolytically processed to generate the mature cadherin protein. These integral membrane proteins mediate calcium-dependent cell-cell adhesion and are composed of a large N-terminal extracellular domain, a single membrane-spanning domain, and a small, highly conserved C-terminal cytoplasmic domain. Type II (atypical) cadherins are defined based on their lack of a histidine-alanine-valine (HAV) cell adhesion recognition sequence specific to type I cadherins. This particular cadherin appears to be expressed specifically in the brain and its temporal pattern of expression would be consistent with a role during a critical period of neuronal development, perhaps specifically during synaptogenesis.
  • Reactivity
    Human, Mouse
  • Storage Instruction
    -20°C
  • UNSPSC
    12352203