CDK-TCIP1

MedChem Express

CDK-TCIP1

9

Research Use Only

C48H62ClN11O8S2

1020.66

CDK-TCIP1 is a bivalent molecule linking CDK9 inhibitor SNS-032 (HY-10008) to BCL6 ligand BI3812 (HY-111381). CDK-TCIP1 potently and specifically kills BCL6-overexpressing cells with EC50 of 7.7 nM for SUDHL5 cells[1].

CC(C)(C1=CN=C(CSC2=CN=C(NC(C3CCN(C(CCCCCCNC(C(CC4)CCN4C5=NC=C(Cl)C(NC6=CC(C=C(OCC(NC)=O)C(N7C)=O)=C7C(OC)=C6)=N5)=O)=O)CC3)=O)S2)O1)C

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