CDK2 degrader 1

MedChem Express

CDK2 degrader 1

5

Research Use Only

99.70

C23H27F2N3O4

447.47

CDK2 degrader 1 (Compound 3) is an orally active cyclin-dependent kinase 2 (CDK2) degrader based on PROTAC technology. CDK2 degrader 1 binds to cereblon to induce ubiquitination and subsequent proteasomal degradation of the CDK2 . CDK2 degrader 1 is used in the research of a wide range of cancers (Red: spiro[3.3]heptan-2- ylmethyl carbonochloridate; Blue: N,N-diisopropylethylamine; Black: linker) [1] .

[H][C@](C1)(CC2)C[C@]2([H])[C@@H]1COC(NC3CN(C4=CC(F)=C(C5C(NC(CC5)=O)=O)C(F)=C4)C3)=O

2°C to 8°C

12352200