CDK2-IN-23 [2488073-20-5]

TargetMol Chemicals

CDK2-IN-23 [2488073-20-5]

16

C20H27F3N6O3S

488.53

CDK2-IN-23 (Compound 17), a selective and highly potent inhibitor of CDK2 (IC 50 = 0.29 nM), demonstrates pharmacodynamic inhibition of CDK2 in CCNE1-amplified mouse models. This compound is utilized in cancer research [1].

C(F)(F)(F)C=1C(=NC(NC2CCN(S(=O)(=O)C3CC3)CC2)=NC1)C4=CN(CC(C)(C)O)N=C4

-20°C

51202000