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CDK8-IN-12

HY-148561
MedChem Express
Molecular Weight381.86
Product group Chemicals

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Overview

  • Supplier
    MedChem Express
  • Product Name
    CDK8-IN-12
  • Delivery Days Customer
    5
  • Molecular Formula
    C21H20ClN3O2
  • Molecular Weight
    381.86
  • Scientific Description
    CDK8-IN-12 is an orally active, potent CDK8 inhibitor with a Ki of 14 nM. CDK8-IN-12 has off-target kinase inhibition on GSK-3alpha, GSK-3beta, PCK-theta with Kis of 13 nM, 4 nM, 109 nM, respectively. CDK8-IN-12 shows potent anti-proliferative effects selectively on MV4-11 cell. CDK8-IN-12 is an anti-cancer agent.
  • SMILES
    O=C1NCCC12CCN(C3=C(C4=CC5=CC=CC=C5O4)C=NC=C3Cl)CC2
  • Storage Instruction
    See Manual
  • UNSPSC
    12352200