CDK8-IN-12
HY-148561
Molecular Weight381.86
Product group Chemicals
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Overview
- SupplierMedChem Express
- Product NameCDK8-IN-12
- Delivery Days Customer5
- Molecular FormulaC21H20ClN3O2
- Molecular Weight381.86
- Scientific DescriptionCDK8-IN-12 is an orally active, potent CDK8 inhibitor with a Ki of 14 nM. CDK8-IN-12 has off-target kinase inhibition on GSK-3alpha, GSK-3beta, PCK-theta with Kis of 13 nM, 4 nM, 109 nM, respectively. CDK8-IN-12 shows potent anti-proliferative effects selectively on MV4-11 cell. CDK8-IN-12 is an anti-cancer agent.
- SMILESO=C1NCCC12CCN(C3=C(C4=CC5=CC=CC=C5O4)C=NC=C3Cl)CC2
- Storage InstructionSee Manual
- UNSPSC12352200