CDK8-IN-13

MedChem Express

CDK8-IN-13

5

99.14%

C14H11N3O

237.26

CDK8-IN-13 is a potent, selective and orally active CDK8 inhibitor with an IC50 value of 51.9 nM. CDK8-IN-13 induces Apoptosis. CDK8-IN-13 decreases the expression of p-STAT1 S727 and p-STAT5 S726. CDK8-IN-13 shows antitumor activity.

O=C(C1=CC=CC(C2=CN=C3NC=CC3=C2)=C1)N

2°C to 8°C,-20°C,-80°C

12352200