CDK8/19-IN-1
T10739
Overview
- SupplierTargetMol Chemicals
- Product NameCDK8/19-IN-1
- Delivery Days Customer65
- CAS Number1818427-07-4
- Category SupplierChemical
- Chemical NameCDK8/19-IN-1
- Molecular FormulaC19H18N4O4S2
- Molecular Weight430.5
- Scientific DescriptionCDK8/19-IN-1 is a selective and oral bioavailable CDK8/19 dual inhibitor (IC50s: 0.46 nM, 0.99 nM, and 270 nM for CDK8, CDK19, and CDK9).
- Shelf life instruction3 years
- SMILESO(C1=C2C(=C(C(N)=O)S1)CCC3=C2SN=C3)C=4C=CC(C(NCCOC)=O)=NC4
- Storage Instruction-20°
- UNSPSC12352200
References
- Ono K, et al. Design and synthesis of selective CDK8/19 dual inhibitors: Discovery of 4,5-dihydrothieno[3',4':3,4]benzo[1,2-d]isothiazole derivatives. Bioorg Med Chem. 2017 Apr 15;25(8):2336-2350.Read more