Bio-Connect

CDKN1C Polyclonal Antibody

Research Use Only
RD82502A
Reddot Biotech
ApplicationsWestern Blot
Product group Antibodies
ReactivityMouse, Rat
TargetCDKN1C
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Overview

  • Supplier
    Reddot Biotech
  • Product Name
    CDKN1C Polyclonal Antibody
  • Delivery Days Customer
    5
  • Applications
    Western Blot
  • Certification
    Research Use Only
  • Concentration
    1 mg/ml
  • Conjugate
    Unconjugated
  • Gene ID1028
  • Target name
    CDKN1C
  • Target description
    cyclin dependent kinase inhibitor 1C
  • Target synonyms
    BWCR; BWS; cyclin-dependent kinase inhibitor 1C; cyclin-dependent kinase inhibitor 1C (p57, Kip2); cyclin-dependent kinase inhibitor p57; KIP2; p57; p57Kip2; WBS
  • Host
    Rabbit
  • Isotype
    IgG
  • Scientific Description
    This gene is imprinted, with preferential expression of the maternal allele. The encoded protein is a tight-binding, strong inhibitor of several G1 cyclin/Cdk complexes and a negative regulator of cell proliferation. Mutations in this gene are implicated in sporadic cancers and Beckwith-Wiedemann syndorome, suggesting that this gene is a tumor suppressor candidate. Three transcript variants encoding two different isoforms have been found for this gene.
  • Reactivity
    Mouse, Rat
  • Storage Instruction
    -20°C
  • UNSPSC
    12352203