CDKN1C Polyclonal Antibody
RD82502A
ApplicationsWestern Blot
Product group Antibodies
ReactivityMouse, Rat
TargetCDKN1C
Overview
- SupplierReddot Biotech
- Product NameCDKN1C Polyclonal Antibody
- Delivery Days Customer5
- ApplicationsWestern Blot
- CertificationResearch Use Only
- Concentration1 mg/ml
- ConjugateUnconjugated
- Gene ID1028
- Target nameCDKN1C
- Target descriptioncyclin dependent kinase inhibitor 1C
- Target synonymsBWCR; BWS; cyclin-dependent kinase inhibitor 1C; cyclin-dependent kinase inhibitor 1C (p57, Kip2); cyclin-dependent kinase inhibitor p57; KIP2; p57; p57Kip2; WBS
- HostRabbit
- IsotypeIgG
- Scientific DescriptionThis gene is imprinted, with preferential expression of the maternal allele. The encoded protein is a tight-binding, strong inhibitor of several G1 cyclin/Cdk complexes and a negative regulator of cell proliferation. Mutations in this gene are implicated in sporadic cancers and Beckwith-Wiedemann syndorome, suggesting that this gene is a tumor suppressor candidate. Three transcript variants encoding two different isoforms have been found for this gene.
- ReactivityMouse, Rat
- Storage Instruction-20°C
- UNSPSC12352203