CEA Antibody / Carcinoembryonic Antigen
ORB248297
ApplicationsImmunoHistoChemistry
Product group Antibodies
Overview
- SupplierBiorbyt
- Product NameCEA Antibody / Carcinoembryonic Antigen
- Delivery Days Customer16
- ApplicationsImmunoHistoChemistry
- Applications SupplierImmunohistochemistry (FFPE): 0.25-0.5ug/ml for 30 min at RT IHC-P
- CertificationResearch Use Only
- Clone IDC66/261
- IsotypeIgG
- Scientific DescriptionThis antibody recognizes proteins of 80-200kDa, identified as different members of the CEA (Carcinoembryonic Antigen) family. CEA is synthesized during development in the fetal gut and is re-expressed in increased amounts in intestinal carcinomas and several other tumors. This antibody does not react with nonspecific cross-reacting antigen (NCA) and with human polymorphonuclear leucocytes. The antibody shows no reaction with a variety of normal tissues and is suitable for staining of formalin/paraffin tissues. CEA is not found in benign glands, stroma, or malignant prostatic cells. antibody to CEA is useful in detecting early foci of gastric carcinoma and in distinguishing pulmonary adenocarcinomas (60-70% are CEA+) from pleural mesotheliomas (rarely or weakly CEA+). CEA antibody positivity is seen in adenocarcinomas from the lung, colon, stomach, esophagus, pancreas, gallbadder, urachus, salivary gland, ovary, and endocervix.
- UNSPSC12352203