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CEACAM5 Protein, Cynomolgus, Recombinant (aa 35-685, His)

CEACAM5 Protein, Cynomolgus, Recombinant (aa 35-685, His)

TMPK-01299
TargetMol Chemicals
Molecular Weight72.76 kDa (predicted). Due to glycosylation, the protein migrates to 120-200 kDa based on Tris-Bis PAGE result.
Product group Chemicals
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Overview

  • Supplier
    TargetMol Chemicals
  • Product Name
    CEACAM5 Protein, Cynomolgus, Recombinant (aa 35-685, His)
  • Delivery Days Customer
    16
  • Certification
    Research Use Only
  • Molecular Weight
    72.76 kDa (predicted). Due to glycosylation, the protein migrates to 120-200 kDa based on Tris-Bis PAGE result.
  • Scientific Description
    Carcinoembryonic antigen-related cell adhesion molecule 5 (CEACAM5) was identified as a metastatic driver. CEACAM5 overproduction enriched for an epithelial gene expression pattern and facilitated tumor outgrowth at metastatic sites. Tissues from patients with metastatic breast cancer confirmed elevated levels of CEACAM5 in lung metastases relative to breast tumors, and an inverse correlation between CEACAM5 and the mesenchymal marker vimentin was demonstrated.
  • Storage Instruction
    -20°C
  • UNSPSC
    12352200