Cediranib maleate

AbMole BioScience

Cediranib maleate

9

857036-77-2

Chemical

566.58

Cediranib maleate (AZD-2171 maleate) is a highly potent, orally available VEGFR inhibitor with IC50s of <1, <3, 5, 5, 36, 2 nM for Flt1, KDR, Flt4, PDGFRalfa, PDGFRbèta, c-Kit, respectively.

COC1=CC2=C(OC3=C(F)C4=C([NH]C(=C4)C)C=C3)N=CN=C2C=C1OCCCN5CCCC5.OC(=O)\C=C/C(O)=O

2-8°C, dry, sealed

12352200