NF-kappaB reporter (Luc) - HEK293 Cell line

BPS Bioscience

NF-kappaB reporter (Luc) - HEK293 Cell line

7

Research Use Only

The NF-kappaB reporter (Luc) HEK293 cell line is designed to monitor nuclear factor Kappa B (NF-kappaB) activity. It contains a firefly luciferase gene driven by four copies of the NF-kappaB response element located upstream of the minimal TATA promoter. After activation by pro-inflammatory cytokines or agonists of lymphokine receptors, endogenous NF-kappaB transcription factors bind to the DNA response elements, inducing transcription of the luciferase reporter gene. The cell line has been functionally validated in response to human TNF-alpha, IL-1beta, and IL-17.

Liquid Nitrogen

41116155