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CEP-14083

Research Use Only
HY-14243
MedChem Express
Molecular Weight518.61
Product group Chemicals
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Overview

  • Supplier
    MedChem Express
  • Product Name
    CEP-14083
  • Delivery Days Customer
    9
  • Certification
    Research Use Only
  • Molecular Formula
    C31H30N6O2
  • Molecular Weight
    518.61
  • Scientific Description
    CEP-14083 is a ATP-competitive ALK kinase inhibitor with an IC50 value in enzymatic assays of 2 nM. CEP-14083 also inhibits other kinases, such as insulin receptor (IR), vascular endothelial growth factor receptor 2 (VEGFR2), angiopoietin-1 receptor (TIE2) and dual leucine zipper kinase (DLK). CEP-14083 suppresses CD274 mRNA expression and the NPM/ALK function in the NPM/ALK-carrying T cell lymphoma (ALK+TCL) cells. CEP-14083 is promising for research of lymphoma[1][2].
  • SMILES
    CN1N=C2CCC3=C4N(C5=CC=C(C=C5C4=C(CNC6=O)C6=C3C2=C1)NC(N(C7=CC=CC=C7)C)=O)CCC
  • UNSPSC
    12352200