CEP290 Antibody, Biotin conjugated
CSB-PA005241LD01HU
ApplicationsELISA
Product group Antibodies
ReactivityHuman
TargetCEP290
Overview
- SupplierCusabio
- Product NameCEP290 Antibody, Biotin conjugated
- Delivery Days Customer20
- ApplicationsELISA
- CertificationResearch Use Only
- ClonalityPolyclonal
- ConjugateBiotin
- Gene ID80184
- Target nameCEP290
- Target descriptioncentrosomal protein 290
- Target synonyms3H11Ag; Bardet-Biedl syndrome 14 protein; BBS14; cancer/testis antigen 87; centrosomal protein 290kDa; centrosomal protein of 290 kDa; CT87; CTCL tumor antigen se2-2; JBTS5; LCA10; Meckel syndrome, type 4; MKS4; monoclonal antibody 3H11 antigen; nephrocytsin-6; NPHP6; POC3; POC3 centriolar protein homolog; prostate cancer antigen T21; rd16; SLSN6; tumor antigen se2-2
- HostRabbit
- IsotypeIgG
- Protein IDO15078
- Protein NameCentrosomal protein of 290 kDa
- Scientific DescriptionInvolved in early and late steps in cilia formation. Its association with CCP110 is required for inhibition of primary cilia formation by CCP110 (PubMed:18694559). May play a role in early ciliogenesis in the disappearance of centriolar satellites and in the transition of primary ciliar vesicles (PCVs) to capped ciliary vesicles (CCVs). Required for the centrosomal recruitment of RAB8A and for the targeting of centriole satellite proteins to centrosomes such as of PCM1 (PubMed:24421332). In the ciliary transition zone is part of the tectonic-like complex which is required for tissue-specific ciliogenesis and may regulate ciliary membrane composition (By similarity). Involved in regulation of the BBSome complex integrity, specifically for presence of BBS2, BBS5 and BBS8/TTC8 in the complex, and in ciliary targeting of selected BBSome cargos. May act as a gatekeeper to control entry of the BBSome complex to cilia (PubMed:25552655). Required for the correct localization of ciliary and phototransduction proteins in retinal photoreceptor cells; may play a role in ciliary transport processes (By similarity). Activates ATF4-mediated transcription (PubMed:16682973).
- ReactivityHuman
- Storage Instruction-20°C or -80°C
- UNSPSC12352203