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ProductsBack/CEP57 antibody [N1C1]

CEP57 antibody [N1C1]

GTX115931
GeneTex
ApplicationsImmunoFluorescence, ImmunoPrecipitation, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
DownloadDatasheet
Product group Antibodies
ReactivityHuman
TargetCEP57
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Overview

  • Supplier
    GeneTex
  • Product Name
    CEP57 antibody [N1C1]
  • Delivery Days Customer
    9
  • Application Supplier Note
    IHC-P: 1:100-1:1000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
  • Applications
    ImmunoFluorescence, ImmunoPrecipitation, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
  • Certification
    Research Use Only
  • Clonality
    Polyclonal
  • Concentration
    1.51 mg/ml
  • Conjugate
    Unconjugated
  • Gene ID9702
  • Target name
    CEP57
  • Target description
    centrosomal protein 57
  • Target synonyms
    centrosomal protein 57kDa; centrosomal protein of 57 kDa; FGF2-interacting protein; MVA2; PIG8; proliferation-inducing protein 8; testis-specific protein 57; translokin; TSP57
  • Host
    Rabbit
  • Isotype
    IgG
  • Protein IDQ86XR8
  • Protein Name
    Centrosomal protein of 57 kDa
  • Scientific Description
    Translokin binds basic fibroblast growth factor (FGF2; MIM 134920) and mediates its nuclear translocation and mitogenic activity (Bossard et al., 2003 [PubMed 12717444]).[supplied by OMIM]
  • Reactivity
    Human
  • Storage Instruction
    -20°C or -80°C,2°C to 8°C
  • UNSPSC
    12352203

References

  • Mild replication stress causes premature centriole disengagement via a sub-critical Plk1 activity under the control of ATR-Chk1.
    Read more
  • Centrosomal organization of Cep152 provides flexibility in Plk4 and procentriole positioning.
    Read more
  • The APC/C targets the Cep152-Cep63 complex at the centrosome to regulate mitotic spindle assembly. Tischer T et al., 2022 Jan 15, J Cell Sci
    Read more
  • Cep57 and Cep57L1 maintain centriole engagement in interphase to ensure centriole duplication cycle. Ito KK et al., 2021 Mar 1, J Cell Biol
    Read more
  • The Cep57-pericentrin module organizes PCM expansion and centriole engagement. Watanabe K et al., 2019 Feb 25, Nat Commun
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  • Cep57 is a Mis12-interacting kinetochore protein involved in kinetochore targeting of Mad1-Mad2. Zhou H et al., 2016 Jan 8, Nat Commun
    Read more