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CEP57 antibody [N1C1]

Name: CEP57 antibody [N1C1]
SKU: GTX115931_G10
Availability: BackOrder

GTX115931

ApplicationsImmunoFluorescence, ImmunoPrecipitation, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin

Product group Antibodies

TargetCEP57

Overview

Supplier
GeneTex
Product Name
CEP57 antibody [N1C1]
Delivery Days Customer
9
Application Supplier Note
IHC-P: 1:100-1:1000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
Applications
ImmunoFluorescence, ImmunoPrecipitation, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
Certification
Research Use Only
Clonality
Polyclonal
Concentration
1.51 mg/ml
Conjugate
Unconjugated
Gene ID9702
Target name
CEP57
Target description
centrosomal protein 57
Target synonyms
MVA2, PIG8, TSP57, centrosomal protein of 57 kDa, FGF2-interacting protein, centrosomal protein 57kDa, proliferation-inducing protein 8, testis-specific protein 57, translokin
Host
Rabbit
Isotype
IgG
Protein IDQ86XR8
Protein Name
Centrosomal protein of 57 kDa
Scientific Description
Translokin binds basic fibroblast growth factor (FGF2; MIM 134920) and mediates its nuclear translocation and mitogenic activity (Bossard et al., 2003 [PubMed 12717444]).[supplied by OMIM]
Storage Instruction
-20°C or -80°C,2°C to 8°C
UNSPSC
12352203

Dwivedi D, Harry D, Meraldi P. Mild replication stress causes premature centriole disengagement via a sub-critical Plk1 activity under the control of ATR-Chk1. Nat Commun. 2023,14(1):6088. doi: 10.1038/s41467-023-41753-1
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Sullenberger C, Kong D, Avazpour P, et al. Centrosomal organization of Cep152 provides flexibility in Plk4 and procentriole positioning. J Cell Biol. 2023,222(12). doi: 10.1083/jcb.202301092
Read this paper
Tischer T, Yang J, Barford D. The APC/C targets the Cep152-Cep63 complex at the centrosome to regulate mitotic spindle assembly. J Cell Sci. 2022,135(2). doi: 10.1242/jcs.259273
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Ito KK, Watanabe K, Ishida H, et al. Cep57 and Cep57L1 maintain centriole engagement in interphase to ensure centriole duplication cycle. J Cell Biol. 2021,220(3). doi: 10.1083/jcb.202005153
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Watanabe K, Takao D, Ito KK, et al. The Cep57-pericentrin module organizes PCM expansion and centriole engagement. Nat Commun. 2019,10(1):931. doi: 10.1038/s41467-019-08862-2
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Zhou H, Wang T, Zheng T, et al. Cep57 is a Mis12-interacting kinetochore protein involved in kinetochore targeting of Mad1-Mad2. Nat Commun. 2016,7:10151. doi: 10.1038/ncomms10151
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