Cerdulatinib (hydrochloride)

MedChem Express

Cerdulatinib (hydrochloride) [1369761-01-2]

10

1369761-01-2

Research Use Only

99.89

C20H28ClN7O3S

482.00

Cerdulatinib hydrochloride (PRT062070) is a selective, oral active and reversible ATP-competitive inhibitor of dual SYK and JAK , with IC 50 s of 32 nM, 0.5 nM, 12 nM, 6 nM and 8 nM for SYK and Tyk2 , JAK1 , 2 , 3 , respectively. Cerdulatinib hydrochloride could be used to research autoimmune disease and B-cell malignancies [1] [2] .

O=S(N(CC1)CCN1C2=CC=C(NC3=NC=C(C(N)=O)C(NC4CC4)=N3)C=C2)(CC)=O.Cl

-20°C,2°C to 8°C

12352200