CFD Polyclonal Antibody
RD84915A
ApplicationsImmunoHistoChemistry
Product group Antibodies
ReactivityHuman, Mouse
TargetCFD
Overview
- SupplierReddot Biotech
- Product NameCFD Polyclonal Antibody
- Delivery Days Customer5
- ApplicationsImmunoHistoChemistry
- CertificationResearch Use Only
- Concentration1 mg/ml
- ConjugateUnconjugated
- Gene ID1675
- Target nameCFD
- Target descriptioncomplement factor D
- Target synonymsADIPSIN; ADN; C3 convertase activator; complement factor D; complement factor D preproprotein; D component of complement (adipsin); DF; PFD; properdin factor D
- HostRabbit
- IsotypeIgG
- Scientific DescriptionThis gene encodes a member of the S1, or chymotrypsin, family of serine peptidases. This protease catalyzes the cleavage of factor B, the rate-limiting step of the alternative pathway of complement activation. This protein also functions as an adipokine, a cell signaling protein secreted by adipocytes, which regulates insulin secretion in mice. Mutations in this gene underlie complement factor D deficiency, which is associated with recurrent bacterial meningitis infections in human patients. Alternative splicing of this gene results in multiple transcript variants. At least one of these variants encodes a preproprotein that is proteolytically processed to generate the mature protease.
- ReactivityHuman, Mouse
- Storage Instruction-20°C
- UNSPSC12352203