
Western blot analysis of extracts from Jurkat cells and HeLa cells, using Cofilin antibody.
CFL1/CFL2 Antibody
CSB-PA077671
ApplicationsWestern Blot, ELISA
Product group Antibodies
ReactivityHuman, Mouse, Rat
TargetCFL1
Overview
- SupplierCusabio
- Product NameCFL1/CFL2 Antibody
- Delivery Days Customer20
- ApplicationsWestern Blot, ELISA
- CertificationResearch Use Only
- ClonalityPolyclonal
- ConjugateUnconjugated
- Gene ID1072
- Target nameCFL1
- Target descriptioncofilin 1
- Target synonyms18 kDa phosphoprotein; CFL; cofilin; cofilin 1 (non-muscle); cofilin-1; epididymis secretory protein Li 15; HEL-S-15; p18
- HostRabbit
- IsotypeIgG
- Protein IDP23528
- Protein NameCofilin-1
- Scientific DescriptionBinds to F-actin and exhibits pH-sensitive F-actin depolymerizing activity. Regulates actin cytoskeleton dynamics. Important for normal progress through mitosis and normal cytokinesis. Plays a role in the regulation of cell morphology and cytoskeletal organization. Required for the up-regulation of atypical chemokine receptor ACKR2 from endosomal compartment to cell membrane, increasing its efficiency in chemokine uptake and degradation. Thirion C., Eur. J. Biochem. 268:3473-3482(2001). Zhang Y., Mol. Cell. Proteomics 4:1240-1250(2005). Olsen J.V., Cell 127:635-648(2006).
- ReactivityHuman, Mouse, Rat
- Storage Instruction-20°C or -80°C
- UNSPSC12352203