CFL1/CFL2 Antibody

Cusabio

CFL1/CFL2 Antibody

20

Western Blot, ELISA

Research Use Only

Polyclonal

Unconjugated

Rabbit

IgG

Binds to F-actin and exhibits pH-sensitive F-actin depolymerizing activity. Regulates actin cytoskeleton dynamics. Important for normal progress through mitosis and normal cytokinesis. Plays a role in the regulation of cell morphology and cytoskeletal organization. Required for the up-regulation of atypical chemokine receptor ACKR2 from endosomal compartment to cell membrane, increasing its efficiency in chemokine uptake and degradation. Thirion C., Eur. J. Biochem. 268:3473-3482(2001). Zhang Y., Mol. Cell. Proteomics 4:1240-1250(2005). Olsen J.V., Cell 127:635-648(2006).

Human, Mouse, Rat

-20°C or -80°C

12352203