cGAMP (disodium)

MedChem Express

cGAMP (disodium) [2407516-83-8]

10

2407516-83-8

Research Use Only

98.47

C20H22N10Na2O13P2

718.37

cGAMP (Cyclic GMP-AMPP) disodium functions as an endogenous second messenger in metazoans and triggers interferon production in response to cytosolic DNA. cGAMP diammonium activates stimulator of interferon genes (STING) , which activates a signaling cascade leading to the production of type I interferons and other immune mediators [1] [2] [3] [4] .

[H][C@@]12COP(O[C@]3([C@H]([C@H](N4C=NC5=C(N=CN=C45)N)O[C@@]3(COP(O[C@]1([C@H]([C@H](N6C=NC7=C6N=C(N)NC7=O)O2)O)[H])(O[Na])=O)[H])O)[H])(O[Na])=O

-20°C

12352200