cGAS-IN-1 [858770-07-7]

TargetMol Chemicals

cGAS-IN-1 [858770-07-7]

16

Chemical

Research Use Only

cGAS-IN-1

C18H19NO8

377.35

cGAS-IN-1 (compound C20), a flavonoid that acts as a Cyclic GMP-AMP Synthase (cGAS) inhibitor, demonstrates IC50 values of 2.28 microM for human cGAS and 1.44 microM for mouse cGAS. By inhibiting the abnormal activation of cGAS linked to numerous immune-mediated inflammatory diseases, cGAS-IN-1 possesses potential anti-inflammatory properties [1].

3 years

COC1=CC=C2C(OC(=O)C(CCC(=O)N(CC(O)=O)CC(O)=O)=C2C)=C1

-20°C

51202000