CGGBP1 Polyclonal Antibody

Reddot Biotech

CGGBP1 Polyclonal Antibody

5

Western Blot

Research Use Only

1 mg/ml

Unconjugated

CGGBP1

CGG triplet repeat binding protein 1

20 kDa CGG-binding protein; CGG triplet repeat-binding protein 1; CGG-binding protein 1; CGGBP; p20-CGG binding protein; p20-CGGBP; p20-CGGBP DNA-binding protein

Rabbit

IgG

This gene encodes a CGG repeat-binding protein that primarily localizes to the nucleus. CGG trinucleotide repeats are implicated in many disorders as they often act as transcription- and translation-regulatory elements, can produce hairpin structures which cause DNA replication errors, and form regions prone to chromosomal breakage. CGG repeats are also targets for CpG methylation. In addition to its ability to bind CGG repeats and regulate transcription, this gene is believed to play a role in DNA damage repair and telomere protection. In vitro studies indicate this protein does not bind to methylated CpG sequences.

Human

-20°C

12352203