CGI-1746 [910232-84-7]

Biorbyt

CGI-1746 [910232-84-7]

16

910232-84-7

Research Use Only

C34H37N5O4

579.6887

CGI1746 is a small-molecule Btk inhibitor chemotype with a new binding mode that stabilizes an inactive nonphosphorylated enzyme conformation.

O1C([H])([H])C([H])([H])N(C(C2C([H])=C([H])C(=C([H])C=2[H])N([H])C2C(N(C([H])([H])[H])C([H])=C(C3C([H])=C([H])C([H])=C(C=3C([H])([H])[H])N([H])C(C3C([H])=C([H])C(=C([H])C=3[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])=O)N=2)=O)=O)C([H])([H])C1([H])[H]

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