CGP-28014 [111757-17-6]

TargetMol Chemicals

CGP-28014 [111757-17-6]

72

Chemical

Research Use Only

CGP-28014

C12H19N3O

221.3

CGP-28014 is an inhibitor of catechol-O-methyltransferase. CGP-28014 increases the renal excretion of both dopamine and dihydroxyphenylacetic acid (DOPAC) but does not affect renal sodium handling indicating a different mechanism of action. CGP-28014 significantly reduced the levels of homovanillic acid (HVA), but did not modify DA and 3,4-dihydroxyphenylacetic acid (DOPAC).

3 years

N(=CN(CCC)CCC)C=1NC(=O)C=CC1

-20°C

12352200