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ProductsBack/CGRP antibody [4901]
Immunostaining of CGRP (red) in cryopreserved DRG neurons grown on coverslips. 40xmag. Green staining is PGP9.5. Yellow staining is the colocalization of CGRP and PGP9.5.
Immunostaining of CGRP (red) in cryopreserved DRG neurons grown on coverslips. 40xmag. Green staining is PGP9.5. Yellow staining is the colocalization of CGRP and PGP9.5.
Immunostaining of CGRP (red) in cryopreserved DRG neurons grown on coverslips. 40xmag. Green staining is PGP9.5. Yellow staining is the colocalization of CGRP and PGP9.5.

CGRP antibody [4901]

GTX82726
GeneTex
ApplicationsImmunoFluorescence, Western Blot, ELISA, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Frozen, Neutralisation/Blocking, RadioImmunoAssay
DownloadDatasheet
Product group Antibodies
ReactivityCanine, Human, Mouse, Rat
TargetCalca
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Overview

  • Supplier
    GeneTex
  • Product Name
    CGRP antibody [4901]
  • Delivery Days Customer
    9
  • Application Supplier Note
    Optimal working dilutions should be determined experimentally by the end user.
  • Applications
    ImmunoFluorescence, Western Blot, ELISA, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Frozen, Neutralisation/Blocking, RadioImmunoAssay
  • Certification
    Research Use Only
  • Clonality
    Monoclonal
  • Clone ID
    4901
  • Conjugate
    Unconjugated
  • Gene ID24241
  • Target name
    Calca
  • Target description
    calcitonin-related polypeptide alpha
  • Target synonyms
    alpha-type CGRP; Cal1; CAL6; Calc; calcitonin; calcitonin gene-related peptide 1; calcitonin gene-related peptide I; calcitonin/calcitonin-related polypeptide, alpha; CGRP; CGRP-I; procalcitonin; RATCAL6
  • Host
    Mouse
  • Isotype
    IgG2a
  • Scientific Description
    CGRP induces vasodilation. It dilates a variety of vessels including the coronary, cerebral and systemic vasculature. Its abundance in the CNS also points toward a neurotransmitter or neuromodulator role.
  • Reactivity
    Canine, Human, Mouse, Rat
  • Storage Instruction
    -20°C or -80°C,2°C to 8°C
  • UNSPSC
    12352203

References

  • KDM6B epigenetically regulated-interleukin-6 expression in the dorsal root ganglia and spinal dorsal horn contributes to the development and maintenance of neuropathic pain following peripheral nerve injury in male rats. Li L et al., 2021 Nov, Brain Behav Immun
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  • Anatomical Evidence for a Direct Projection from Purkinje Cells in the Mouse Cerebellar Vermis to Medial Parabrachial Nucleus.
    Read more
  • New mechanism underlying IL-31-induced atopic dermatitis.
    Read more
  • Morphology and connectivity of parabrachial and cortical inputs to gustatory thalamus in rats.
    Read more
  • Sensory innervation of the dorsal longitudinal ligament and the meninges in the lumbar spine of the dog.
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  • Effect of CGRP-adenoviral vector transduction on the osteoblastic differentiation of rat adipose-derived stem cells. Fang Z et al., 2013, PLoS One
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  • Evidence for anti-inflammatory and putative analgesic effects of a monoclonal antibody to calcitonin gene-related peptide.
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  • CGRP function-blocking antibodies inhibit neurogenic vasodilatation without affecting heart rate or arterial blood pressure in the rat.
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  • Monoclonal antibody to rat alpha-CGRP: production, characterization, and in vivo immunoneutralization activity.
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