CGS25155

MedChem Express

CGS25155

9

Research Use Only

C25H34N2O6S

490.61

CGS25155 is an orally active neutral endopeptidase 24.11 ( NEP 24.11 ) inhibitor with an IC 50 of 3 nM. CGS25155 can slow down the degradation of the cardiac hormone atrial natriuretic peptide (ANP) and exhibits antihypertensive activity in the DOCA-salt induced rat hypertension model. CGS25155 can be used in cardiovascular disease research [1] .

O=C([C@H]1NC([C@@H](CCCCCC1)CSC(C)=O)=O)N2[C@@H](C[C@H](C2)O)C(OCC3=CC=CC=C3)=O

12352200