CH-0793076 (TFA)

MedChem Express

CH-0793076 (TFA)

9

Research Use Only

98.71

C28H27F3N4O6

572.53

CH-0793076 (TP3076) TFA, a hexacyclic camptothecin analog, is active drug and major metabolite of TP300. CH-0793076 TFA inhibits DNA topoisomerase I with an IC 50 of 2.3 microM. CH-0793076 TFA is efficacious against cells expressing BCRP (breast cancer resistance protein) [1] .

O=C1[C@](O)(CC)C(C=C23)=C(CO1)C(N2CC(C3=N4)=C5N(CCCCC)C=NC6=C5C4=CC=C6)=O.O=C(O)C(F)(F)F

2°C to 8°C

12352200