CHDI-00484077

MedChem Express

CHDI-00484077 [3025894-92-9]

5

Research Use Only

C18H21F3N4O2

382.38

CHDI-00484077 (Compound 12) is a CNS-penetrant class IIa HDAC inhibitor, with IC50s of 0.01 microM (HDAC4), 0.02 microM(HDAC5), 0.02 microM (HDAC7), 0.03 microM (HDAC9) respectively. CHDI-00484077 can be used for research of huntingtons disease[1].

FC(F)(C1=NC(C2=CC=C(C=C2)C(N[C@H](C)CN3[C@H](CCC3)C)=O)=NO1)F

12131703