Chelerythrine
HY-N2359
CAS Number34316-15-9
Product group Chemicals
Molecular Weight348.37
Overview
- SupplierMedChem Express
- Product NameChelerythrine
- Delivery Days Customer10
- CAS Number34316-15-9
- CertificationResearch Use Only
- Molecular FormulaC21H18NO4
- Molecular Weight348.37
- Scientific DescriptionChelerythrine is a natural alkaloid, acts as a potent and selective Ca2+/phospholopid-dependent PKC antagonist, with an IC50 of 0.7 microM[1]. Chelerythrine has antitumor, antidiabetic and anti-inflammatory activity[2]. Chelerythrine inhibits the BclXL-Bak BH3 peptide binding with IC50 of 1.5 microM and displaces Bax from BclXL. Chelerythrine triggers apoptosis and autophagy[3][4].
- SMILESC[N+]1=CC2=C(OC)C(OC)=CC=C2C(C=CC3=C4)=C1C3=CC5=C4OCO5
- UNSPSC12352200
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