Sotorasib [2296729-00-3]
HY-114277
Overview
- SupplierMedChem Express
- Product NameSotorasib [2296729-00-3]
- Delivery Days Customer10
- CAS Number2296729-00-3
- Estimated Purity98%
- Molecular FormulaC30H30F2N6O3
- Molecular Weight560.59
- Scientific DescriptionSotorasib (AMG-510) is a first-in-class, orally bioavailable, and selective KRAS G12C covalent inhibitor. Sotorasib irreversibly inhibits KRAS G12C by locking it in an inactive GDP-bound state. Sotorasib is the first KRAS G12C inhibitor in clinical development and leads to the regression of KRAS G12C tumors.
- SMILESO=C(C=C)N1C[C@H](C)N(C2=NC(N(C3=C(C)C=CN=C3C(C)C)C4=C2C=C(F)C(C5=C(O)C=CC=C5F)=N4)=O)CC1
- Storage Instruction-20°C,-80°C
- UNSPSC12352200