Find the product you need

News

Arglabin [84692-91-1]

Catalog number: AG-CN2-0458-M001
Brand: AdipoGen Life Sciences
Packing: 1 mg
Other sizes: Other size available
Price: € 80.00
Expected delivery time: 7 days
Quantity:
Spin UpSpin Down
Chemical Structure
Chemical Structure...

Product specifications for - Arglabin [84692-91-1]

Overview: 
Product group: Chemicals
Category: Other
CAS No.: 84692-91-1
Properties: 
Purity: >98%
Molecular Formula: C15H18O3
Molecular weight: 246.3
Datasheet: Datasheet
  Research Use Only
UNSPSC: 12352200
Storage instructions: 2-¦C to 8-¦C, -20-¦C
Scientific information: 
Scientific info: Anticancer compound. Farnesyltransferase inhibitor. Potent anti-inflammatory agent. NF-kappaB inhibitor. Inflammasome inhibitor. Antiatherogenic. Prevents the accumulation of lipid containing plaques in arteries. - Chemical. CAS: 84692-91-1. Formula: C15H18O3. MW: 246.3. Semi-synthetic from parthenolide (AG-CN2-0455), which is isolated from Magnolia grandiflora. Anticancer compound. Farnesyltransferase inhibitor. Potent anti-inflammatory agent. NF-kappaB inhibitor. Inflammasome inhibitor. Antiatherogenic. Prevents the accumulation of lipid containing plaques in arteries.
Safety information: 
MSDS: MSDS
Hazard information: Non-hazardous, Warning
Additional information: 
Synonyms: AG-CN2-0458-M001
In vitro biological activities of arglabin, a sesquiterpene lactone from the Chinese herb Artemisia myriantha Wall: C. Bottex-Gauthier, et al.; Biotechnol. Ther. 4, 77 (1993) Read more
Arglabin-DMA, a plant derived sesquiterpene, inhibits farnesyltransferase: T.E. Shaikenov, et al.; Oncol. Rep. 8, 173 (2001) Read more
Biomimetic semisynthesis of arglabin from parthenolide: J.D. Zhai, et al.; JOC 77, 7103 (2012) Read more
Synthesis and biological evaluation of antitumor-active arglabin derivatives: R. Csuk, et al.; Arch Pharm. 345, 215 (2012) Read more
Sesquiterpene lactones and their derivatives inhibit high glucose-induced NF-kappaB activation and MCP-1 and TGF-beta1 expression in rat mesangial cells: Q.Q. Jia, et al.; Molecules 18, 13061 (2013) Read more
Hemisynthesis of a naturally occurring clinically significant antitumor arglabin from ludartin: S.H. Lone & K.A. Bhat; THL 56, 1908 (2015) Read more
Anti-Inflammatory and antiatherogenic effects of the NLRP3 Inflammasome inhibitor Arglabin in ApoE2.Ki mice fed a high-fat diet: A. Abderrazak, et al.; Circulation 131, 1061 (2015) Read more
See All