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Description
Catalog number
CAS No.
Clone ID
News
Vorige
Volgende
BAY 11-7082 [19542-67-7]
Catalog number:
AG-CR1-0013-M010
Brand:
AdipoGen Life Sciences
Packing:
10 mg
Other sizes:
Other size available
Price:
€ 75.00
Expected delivery time:
7 days
Quantity:
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General
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Chemical Structure
Chemical Structure...
Chemical Structure
Chemical Structure
Product specifications for - BAY 11-7082 [19542-67-7]
Overview:
Product group:
Chemicals
Category:
Other
CAS No.:
19542-67-7
Properties:
Purity:
>99% (NMR)
Molecular Formula:
C10H9NO2S
Molecular weight:
207.3
Datasheet:
Datasheet
Research Use Only
UNSPSC:
12352200
Storage instructions:
2-¦C to 8-¦C, -20-¦C
Scientific information:
Scientific info:
Chemical. CAS: 19542-67-7. Formula: C10H9NO2S. MW: 207.3. IkappaBalpha kinase inhibitor. NF-kappaB inhibitor. Potential anti-inflammatory agent. Apoptosis inducer. Inhibits the release of proinflammatory cytokines. NLRP3 inflammasome inhibitor. Reduces ATPase activity of the NLRP3 inflammasome. Inhibits platelet aggregation. - IkappaBalpha kinase inhibitor. NF-kappaB inhibitor. Potential anti-inflammatory agent. Apoptosis inducer. Inhibits the release of proinflammatory cytokines. NLRP3 inflammasome inhibitor. Reduces ATPase activity of the NLRP3 inflammasome. Inhibits platelet aggregation.
Safety information:
MSDS:
MSDS
Hazard information:
Non-hazardous
Additional information:
Synonyms:
AG-CR1-0013-M010
Novel inhibitor of cytokine-induced IkBa phosphorylation and endothelial cell adhesion molecule expression show anti-inflammatory effects in vivo: J.W. Pierce, et al.; J. Biol. Chem. 272, 21096 (1997)
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Bay 11-7082 inhibits transcription factor NF-kappaB and induces apoptosis of HTLV-I-infected T-cell lines and primary adult T-cell leukemia cells: N. Mori, et al.; Blood 100, 1828 (2002)
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Sulfasalazine and BAY 11-7082 interfere with the nuclear factor-kappa B and I kappa B kinase pathway to regulate the release of proinflammatory cytokines from human adipose tissue and skeletal muscle in vitro: M. Lappas et al.; Endocrinology 146, 1491 (2005)
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Anti-inflammatory compounds parthenolide and Bay 11-7082 are direct inhibitors of the inflammasome: C. Juliana, et al.; J. Biol. Chem. 285, 9792 (2010)
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A noble function of BAY 11-7082: Inhibition of platelet aggregation mediated by an elevated cAMP-induced VASP, and decreased ERK2/JNK1 phosphorylations: H.S. Lee, et al.; Eur. J. Pharmacol. 627, 85 (2010)
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