Chemical Structure
Chemical Structure
Compound 34 [564462-36-8]
AG-CR1-0007
CAS Number564462-36-8
Product group Chemicals
Estimated Purity>98% (NMR)
Molecular Weight543.5
Overview
- SupplierAdipoGen Life Sciences
- Product NameCompound 34 [564462-36-8]
- Delivery Days Customer10
- CAS Number564462-36-8
- CertificationResearch Use Only
- Estimated Purity>98% (NMR)
- Hazard InformationNon-hazardous
- Molecular FormulaC31H24F3N3O3
- Molecular Weight543.5
- Scientific DescriptionCell permeable, highly potent inhibitor of gamma-secretase (IC50 = 0.06 nM) [1]. - Chemical. CAS: 564462-36-8. Formula: C31H24F3N3O3. MW: 543.5. Cell permeable, highly potent inhibitor of gamma-secretase (IC50 = 0.06 nM).
- SMILESOC[C@H]([C@H](C(=O)N[C@H]1N=C(C2=CC=CC=C2)C2=C(NC1=O)C=CC=C2)C1=CC=C(F)C=C1)C1=CC=C(F)C(F)=C1
- Storage Instruction2°C to 8°C,-20°C
- UNSPSC12352200
References
- Design and synthesis of highly potent benzodiazepine gamma-secretase inhibitors: preparation of (2S,3R)-3-(3,4-difluorophenyl)-2-(4-fluorophenyl)-4- hydroxy-N-((3S)-1-methyl-2-oxo-5- phenyl-2,3-dihydro-1H-benzo[e][1,4]-diazepin-3-yl)butyramide by use of an asymmetric Ireland-Claisen rearrangement: I. Churcher, et al.; J. Med. Chem 46 2275 (2003)