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Dynasore [1202867-00-2, 304448-55-3]

Catalog number: AG-CR1-0045-M005
Brand: AdipoGen Life Sciences
Packing: 5 mg
Other sizes: Other size available
Price: € 45.00
Expected delivery time: 7 days
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Chemical Structure
Chemical Structure...

Product specifications for - Dynasore [1202867-00-2, 304448-55-3]

Overview: 
Product group: Chemicals
Category: Other
CAS No.: 1202867-00-2
Properties: 
Purity: >98% (NMR)
Molecular Formula: C18H14N2O4 . 0.5H2O
Molecular weight: 322.3 . 9.0
Datasheet: Datasheet
  Research Use Only
UNSPSC: 12352200
Storage instructions: 2-¦C to 8-¦C, -20-¦C
Scientific information: 
Scientific info: Chemical. CAS: 304448-55-3 (free base) 1202867-00-2 (x H2O). Formula: C18H14N2O4 . 0.5H2O. MW: 322.3 . 9.0. Dynamin-1, -2 (DNM1, DNM2) and Dynamin-related protein 1 (DRP1) inhibitor. Endocytosis inhibitor. Viral infection inhibitor. Destabilizes actin filaments. Inhibits entry of Trypanosoma into macrophages. Inhibitor of mitophagy. Inhibitor of hepatocyte lipophagy - Dynamin-1, -2 (DNM1, DNM2) and Dynamin-related protein 1 (DRP1) inhibitor. Endocytosis inhibitor. Viral infection inhibitor. Destabilizes actin filaments. Inhibits entry of Trypanosoma into macrophages. Inhibitor of mitophagy. Inhibitor of hepatocyte lipophagy
Safety information: 
ADR klasse: 9
UN Number: UN 3077
MSDS: MSDS
Hazard information: Excepted quantity, Warning
Additional information: 
Synonyms: AG-CR1-0045-M005
Dynasore, a cell-permeable inhibitor of dynamin.: E. Macia, et al. ; Dev. Cell. 10, 839 (2006) Read more
Use of Dynasore, the Small Molecule Inhibitor of Dynamin, in the Regulation of Endocytosis: T. Kirchhausen, et al.; Meth. Enzymol. 438, 77 (2008) Read more
HPV16 and BPV1 infection can be blocked by the dynamin inhibitor dynasore: C.Y. Abban, et al.; Am. J. Ther. 15, 304 (2008) Read more
Dynasore, a dynamin inhibitor, suppresses lamellipodia formation and cancer cell invasion by destabilizing actin filaments: H. Yamada, et al.; BBRC 390, 1142 (2009) Read more
Dynasore, a dynamin inhibitor, inhibits Trypanosoma cruzi entry into peritoneal macrophages: E.S. Barrias, et al.; PLoS One 5, e7764 (2010) Read more
Mitochondrial dynamics and mitophagy in the 6-hydroxydopamine preclinical model of Parkinson's disease: M.F. Galindo, et al.; Parkinsons Dis. 131058 (2012) Read more
A well-oiled machine: DNM2/dynamin 2 helps keep hepatocyte lipophagy running smoothly: RJ. Schulze & MA. McNiven; Autophagy 10, 388 (2013) Read more
Cadherin-6B undergoes macropinocytosis and clathrin-mediated endocytosis during cranial neural crest cell EMT: R. Padmanabhan & L.A. Taneyhill; J. Cell Sci. 128, 1773 (2015) Read more
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