Bio-Connect

Apitolisib (GDC-0980) [1032754-93-0]

Research Use Only
S2696
Selleck Chemicals
Product group Chemicals
Price on request
Packing Size
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Overview

  • Supplier
    Selleck Chemicals
  • Product Name
    Apitolisib (GDC-0980) [1032754-93-0]
  • Delivery Days Customer
    9
  • Certification
    Research Use Only
  • Scientific Description
    Apitolisib (GDC-0980, RG7422, GNE 390) is a potent, class I PI3K inhibitor for PI3Kalfa/bèta/delta/gamma with IC50 of 5 nM/27 nM/7 nM/14 nM in cell-free assays, respectively. Also a mTOR inhibitor with Ki of 17 nM in a cell-free assay, and highly selective versus other PIKK family kinases. Apitolisib activates autophagy and apoptosis simultaneously in pancreatic cancer cells. Phase 2.
  • UNSPSC
    12352200