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Gefitinib hydrochloride [184475-55-6]

HY-50895A
MedChem Express
CAS Number184475-55-6
Product group Chemicals
Estimated Purity99.55%
Molecular Weight483.36
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Packing Size
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Overview

  • Supplier
    MedChem Express
  • Product Name
    Gefitinib hydrochloride [184475-55-6]
  • Delivery Days Customer
    10
  • CAS Number
    184475-55-6
  • Estimated Purity
    99.55%
  • Molecular Formula
    C22H25Cl2FN4O3
  • Molecular Weight
    483.36
  • Scientific Description
    Gefitinib hydrochloride (ZD1839 hydrochloride) is a potent, selective and orally active EGFR tyrosine kinase inhibitor with an IC50 of 33 nM. Gefitinib hydrochloride selectively inhibits EGF-stimulated tumor cell growth (IC50 of 54 nM) and that blocks EGF-stimulated EGFR autophosphorylation in tumor cells. Gefitinib hydrochloride also induces autophagy. Gefitinib hydrochloride has antitumour activity.
  • SMILES
    ClC1=C(C=CC(NC2=NC=NC3=C2C=C(C(OC)=C3)OCCCN4CCOCC4)=C1)F.[H]Cl
  • Storage Instruction
    2°C to 8°C,-20°C,-80°C
  • UNSPSC
    12352200