Gefitinib hydrochloride [184475-55-6]
HY-50895A
CAS Number184475-55-6
Product group Chemicals
Estimated Purity99.55%
Molecular Weight483.36
Overview
- SupplierMedChem Express
- Product NameGefitinib hydrochloride [184475-55-6]
- Delivery Days Customer10
- CAS Number184475-55-6
- Estimated Purity99.55%
- Molecular FormulaC22H25Cl2FN4O3
- Molecular Weight483.36
- Scientific DescriptionGefitinib hydrochloride (ZD1839 hydrochloride) is a potent, selective and orally active EGFR tyrosine kinase inhibitor with an IC50 of 33 nM. Gefitinib hydrochloride selectively inhibits EGF-stimulated tumor cell growth (IC50 of 54 nM) and that blocks EGF-stimulated EGFR autophosphorylation in tumor cells. Gefitinib hydrochloride also induces autophagy. Gefitinib hydrochloride has antitumour activity.
- SMILESClC1=C(C=CC(NC2=NC=NC3=C2C=C(C(OC)=C3)OCCCN4CCOCC4)=C1)F.[H]Cl
- Storage Instruction2°C to 8°C,-20°C,-80°C
- UNSPSC12352200