IDH-305 [1628805-46-8]
HY-104036
CAS Number1628805-46-8
Product group Chemicals
Estimated Purity98.07%
Molecular Weight490.45
Overview
- SupplierMedChem Express
- Product NameIDH-305 [1628805-46-8]
- Delivery Days Customer10
- CAS Number1628805-46-8
- Estimated Purity98.07%
- Molecular FormulaC23H22F4N6O2
- Molecular Weight490.45
- Scientific DescriptionIDH-305 is an orally available, mutant-selective and brain-penetrant IDH1 inhibitor that targets IDH1 (R132) mutation. IDH-305 exhibits greater than 200 fold selectivity for mutant IDH1 isoforms vs. WT (IC50= 27 nM (IDH1R132H), 28 nM (IDH1R132C), 6.14 microM (IDH1WT)).
- SMILESO=C1OC[C@H]([C@@H](F)C)N1C2=NC(N[C@H](C3=CC(C)=C(C4=CC(C(F)(F)F)=NC=C4)C=N3)C)=NC=C2
- Storage Instruction2°C to 8°C,-20°C,-80°C
- UNSPSC12352200