Tech support
Shopping Cart
Login
Register
Forgot Password?
Products
Diagnostics
Suppliers
About us
Contact
+31 (0)26 326 4450
Find the product you need
Description
Catalog number
CAS No.
Clone ID
News
Vorige
Volgende
Jasplakinolide (high purity) [102396-24-7]
Catalog number:
AG-CN2-0037-C050
Brand:
AdipoGen Life Sciences
Packing:
50 ug
Other sizes:
Other size available
Price:
€ 200.00
Expected delivery time:
7 days
Quantity:
Spin Up
Spin Down
General
Pictures
References
Chemical Structure
Chemical Structure...
Chemical Structure
Chemical Structure
Product specifications for - Jasplakinolide (high purity) [102396-24-7]
Overview:
Product group:
Chemicals
Category:
Other
CAS No.:
102396-24-7
Properties:
Purity:
>98%
Molecular Formula:
C36H45BrN4O6
Molecular weight:
709.7
Datasheet:
Datasheet
Research Use Only
UNSPSC:
12352200
Storage instructions:
2-¦C to 8-¦C, -20-¦C
Scientific information:
Scientific info:
Cell permeable, non-fluorescent F-actin probe. Potent inducer of actin polymerization and stabilization. Competes with phallotoxins for actin binding. Antifungal and antiparasitic compound. Antiproliferative and anticancer compound. Apoptosis enhancer/inducer. Tool used for autophagy/phagocytosis research. - Chemical. CAS: 102396-24-7. Formula: C36H45BrN4O6. MW: 709.7. Isolated from Jaspis splendens. Cell permeable, non-fluorescent F-actin probe. Potent inducer of actin polymerization and stabilization. Competes with phallotoxins for actin binding. Antifungal and antiparasitic compound. Antiproliferative and anticancer compound. Apoptosis enhancer/inducer. Tool used for autophagy/phagocytosis research.
Safety information:
MSDS:
MSDS
Hazard information:
Non-hazardous, Warning
Additional information:
Synonyms:
AG-CN2-0037-C050
Jasplakinolide, a cyclodepsipeptide from the marine sponge, Jaspis sp: P. Crews, et al.; Tetrahedron Lett. 27, 2797 (1986)
Read more
Jaspamide, a modified peptide from a Jaspis sponge, with insecticidal and antifungal activity: T.M. Zabriskie, et al.; JACS 108, 3123 (1986)
Read more
Jasplakinolide, a cytotoxic natural product, induces actin polymerization and competitively inhibits the binding of phalloidin to F-actin: M.R. Bubb, et al.; J. Biol. Chem. 269, 14869 (1994)
Read more
Jasplakinolide's inhibition of the growth of prostate carcinoma cells in vitro with disruption of the actin cytoskeleton: A.M. Senderowicz, et al.; J. Natl. Cancer Inst. 87, 46 (1995)
Read more
Growth modulation and differentiation of acute myeloid leukemia cells by jaspamide: I. Fabian, et al.; Exp. Hematol. 23, 583 (1995)
Read more
Actin stabilization by jasplakinolide enhances apoptosis induced by cytokine deprivation: S.C. Posey & B.E. Bierer; J. Biol. Chem. 274, 4259 (1999)
Read more
Alteration of actin organization by jaspamide inhibits ruffling, but not phagocytosis or oxidative burst, in HL-60 cells and human monocytes: I. Fabian, et al.; Blood 93, 3994 (1999)
Read more
Jasplakinolide. An actin-specific reagent that promotes actin polymerization: A. Holzinger; Methods Mol. Biol. 161, 109 (2001) (Review)
Read more
Effect of jasplakinolide on the growth, invasion, and actin cytoskeleton of Plasmodium falciparum: Y. Mizuno, et al.; Parasitol. Res. 88, 844 (2002)
Read more
Induction of apoptosis and CD10/neutral endopeptidase expression by jaspamide in HL-60 line cells: D.P. Cioca & K. Kitano; Cell. Mol. Life Sci. 59, 1377 (2002)
Read more
See All