Mitapivat [1260075-17-9]

MedChem Express

Mitapivat [1260075-17-9]

10

1260075-17-9

Research Use Only

98.02%

C24H26N4O3S

450.55

Mitapivat (AG-348) is an orally active pyruvate kinase allosteric activator. Mitapivat increases enzymatic activity, protein stability, and ATP levels over a broad range of PKLR genotypes, shows the potential to restore the activity of PK (pyruvate kinase)-deficient glycolytic pathways. Mitapivat can be used in study of PK deficiency.

O=S(C1=C2N=CC=CC2=CC=C1)(NC3=CC=C(C(N4CCN(CC5CC5)CC4)=O)C=C3)=O

2°C to 8°C,-20°C,-80°C

12352200