MS402

MedChem Express

MS402 [1672684-68-2]

10

1672684-68-2

Research Use Only

99.62

C20H19ClN2O3

370.83

MS402 is a BD1 -selective BET BrD inhibitor with K i s of 77 nM, 718 nM, 110 nM, 200 nM, 83 nM, and 240 nM for BRD4(BD1) , BRD4(BD2) , BRD3(BD1) , BRD3(BD2) , BRD2(BD1) and BRD2(BD2) , respectively. MS402 blocks Th17 cell differentiation and ameliorates colitis in mice [1] .

O=C(NC1=CC=C(OC)C=C1)C2=CC=C(NC3=C(C)C(CC3)=O)C(Cl)=C2

-20°C,2°C to 8°C

12352200