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MS402

HY-120000
MedChem Express
CAS Number1672684-68-2
Product group Chemicals
Estimated Purity99.62
Molecular Weight370.83
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Overview

  • Supplier
    MedChem Express
  • Product Name
    MS402 [1672684-68-2]
  • Delivery Days Customer
    10
  • CAS Number
    1672684-68-2
  • Certification
    Research Use Only
  • Estimated Purity
    99.62
  • Molecular Formula
    C20H19ClN2O3
  • Molecular Weight
    370.83
  • Scientific Description
    MS402 is a BD1-selective BET BrD inhibitor with Kis of 77 nM, 718 nM, 110 nM, 200 nM, 83 nM, and 240 nM for BRD4(BD1), BRD4(BD2), BRD3(BD1), BRD3(BD2), BRD2(BD1) and BRD2(BD2), respectively. MS402 blocks Th17 cell differentiation and ameliorates colitis in mice[1].
  • SMILES
    O=C(NC1=CC=C(OC)C=C1)C2=CC=C(NC3=C(C)C(CC3)=O)C(Cl)=C2
  • Storage Instruction
    -20°C,2°C to 8°C
  • UNSPSC
    12352200

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