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MS402

HY-120000
MedChem Express
CAS Number1672684-68-2
Product group Chemicals
Estimated Purity99.62
Molecular Weight370.83
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Overview

  • Supplier
    MedChem Express
  • Product Name
    MS402 [1672684-68-2]
  • Delivery Days Customer
    10
  • CAS Number
    1672684-68-2
  • Certification
    Research Use Only
  • Estimated Purity
    99.62
  • Molecular Formula
    C20H19ClN2O3
  • Molecular Weight
    370.83
  • Scientific Description
    MS402 is a BD1 -selective BET BrD inhibitor with K i s of 77 nM, 718 nM, 110 nM, 200 nM, 83 nM, and 240 nM for BRD4(BD1) , BRD4(BD2) , BRD3(BD1) , BRD3(BD2) , BRD2(BD1) and BRD2(BD2) , respectively. MS402 blocks Th17 cell differentiation and ameliorates colitis in mice [1] .
  • SMILES
    O=C(NC1=CC=C(OC)C=C1)C2=CC=C(NC3=C(C)C(CC3)=O)C(Cl)=C2
  • Storage Instruction
    -20°C,2°C to 8°C
  • UNSPSC
    12352200