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Osimertinib [1421373-65-0]

Research Use Only
HY-15772
MedChem Express
CAS Number1421373-65-0
Product group Chemicals
Estimated Purity99.51%
Molecular Weight499.61
Price on request
Packing Size
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Overview

  • Supplier
    MedChem Express
  • Product Name
    Osimertinib [1421373-65-0]
  • Delivery Days Customer
    10
  • CAS Number
    1421373-65-0
  • Certification
    Research Use Only
  • Estimated Purity
    99.51%
  • Molecular Formula
    C28H33N7O2
  • Molecular Weight
    499.61
  • Scientific Description
    Osimertinib (AZD9291) is a covalent, orally active, irreversible, and mutant-selective EGFR inhibitor with an apparent IC50 of 12 nM against L858R and 1 nM against L858R/T790M, respectively. Osimertinib overcomes T790M-mediated resistance to EGFR inhibitors in lung cancer.
  • SMILES
    C=CC(NC1=CC(NC2=NC=CC(C3=CN(C)C4=C3C=CC=C4)=N2)=C(OC)C=C1N(CCN(C)C)C)=O
  • Storage Instruction
    2°C to 8°C,-20°C,-80°C
  • UNSPSC
    12352200