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Osimertinib-d6 [1638281-44-3]

Research Use Only
HY-15772S
MedChem Express
CAS Number1638281-44-3
Product group Chemicals
Estimated Purity99.7%
Molecular Weight505.64
Price on request
Packing Size
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Overview

  • Supplier
    MedChem Express
  • Product Name
    Osimertinib-d6 [1638281-44-3]
  • Delivery Days Customer
    10
  • CAS Number
    1638281-44-3
  • Certification
    Research Use Only
  • Estimated Purity
    99.7%
  • Molecular Formula
    C28H27D6N7O2
  • Molecular Weight
    505.64
  • Scientific Description
    Osimertinib-d6 is a deuterium labeled osimertinib. Osimertinib is a covalent, orally active, irreversible, and mutant-selective EGFR inhibitor with an apparent IC50 of 12 nM against L858R and 1 nM against L858R/T790M. Osimertinib overcomes T790M-mediated resistance to EGFR inhibitors in lung cancer[1].
  • SMILES
    C=CC(NC1=CC(NC2=NC=CC(C3=CN(C)C4=C3C=CC=C4)=N2)=C(OC)C=C1N(CCN(C([2H])([2H])[2H])C([2H])([2H])[2H])C)=O
  • Storage Instruction
    2°C to 8°C,-20°C,-80°C
  • UNSPSC
    12352200