Osimertinib-d6 [1638281-44-3]
HY-15772S
CAS Number1638281-44-3
Product group Chemicals
Estimated Purity99.7%
Molecular Weight505.64
Overview
- SupplierMedChem Express
- Product NameOsimertinib-d6 [1638281-44-3]
- Delivery Days Customer10
- CAS Number1638281-44-3
- CertificationResearch Use Only
- Estimated Purity99.7%
- Molecular FormulaC28H27D6N7O2
- Molecular Weight505.64
- Scientific DescriptionOsimertinib-d6 is a deuterium labeled osimertinib. Osimertinib is a covalent, orally active, irreversible, and mutant-selective EGFR inhibitor with an apparent IC50 of 12 nM against L858R and 1 nM against L858R/T790M. Osimertinib overcomes T790M-mediated resistance to EGFR inhibitors in lung cancer[1].
- SMILESC=CC(NC1=CC(NC2=NC=CC(C3=CN(C)C4=C3C=CC=C4)=N2)=C(OC)C=C1N(CCN(C([2H])([2H])[2H])C([2H])([2H])[2H])C)=O
- Storage Instruction2°C to 8°C,-20°C,-80°C
- UNSPSC12352200